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Aug 21, 2024

Spatio-Temporal Variability of the Pepper Mild Mottle Virus Biomarker in Wastewater

Since the start of the coronavirus-19 pandemic, the use of wastewater-based epidemiology (WBE) for disease surveillance has increased throughout the world. Because wastewater measurements are affected by external factors, processing...

Apr 29, 2024

Informing policy via dynamic models: Cholera in Haiti

Public health decisions must be made about when and how to implement interventions to control an infectious disease epidemic. These decisions should be informed by data on the epidemic as...

Feb 19, 2024

SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains

Modern multiomic technologies can generate deep multiscale profiles. However, differences in data modalities, multicollinearity of the data, and large numbers of irrelevant features make analyses and integration of high-dimensional omic...

Jun 1, 2023

High-dimensional proteomics identifies organ injury patterns associated with outcomes in human trauma

Severe traumatic injury with shock can lead to direct and indirect organ injury; however, tissue-specific biomarkers are limited in clinical panels. We used proteomic and metabolomic databases to identify organ...

Aug 23, 2022

Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients

Admission-based circulating biomarkers for the prediction of outcomes in trauma patients could be useful for clinical decision support. It is unknown which molecular classes of biomolecules can contribute biomarkers to...

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