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May 22, 2025

Improved Inference For SPLASH

This post builds off my earlier post on concentration inequalities and empirical Bernstein bounds. Here, I’m going to try to apply those ideas to get a better bound on the...

May 21, 2025

Betting-Based Confidence Sequences

A colleague introduced me to some recent work from Waudby-Smith and Ramdas here at Carnegie Mellon. Since I’ve been working on applications of concentration bounds, it certainly seems important to...

May 20, 2025

Martingales

This post works through highlights of Aaditya Ramdas’ 2018 minicourse on martingales at Carnegie Mellon University1 with some supplemental information taken Durrett2 and some definitions from Wikipedia. Additional definitions are...

Apr 30, 2025

Measure Theory

My work has become much more technical that I am used to, so I thought it would be good to take some notes on basic measure and probability theory in...

Feb 27, 2025

SPLASH

There is an exciting new framework for reference-free genomic discovery called SPLASH (Statistically Primary aLignment Agnostic Sequence Homing) from the Salzman Lab at Stanford1 2. It’s super cool, and there...

Feb 20, 2025

Concentration Inequalities

In this post, I’m going to take myself through a review of standard concentration inequalities in probability theory with an ultimate goal of exploring empirical Bernstein bounds. Note: Not all...

Feb 18, 2025

One-Sided Score Test

For some reason, I have not been able to exactly identify what has been going on in my simulations to lead to the strange distributions. My gut tells me it...

Jan 31, 2025

Clustering Stability

My last post related to clustering discussed how to describe a “good” clustering algorithm. One way to measure this is by stability, which I’ll define more rigorously later. The main...

Jan 14, 2025

Clustering: An Axiomatic Approach

Though the journey to this point is a bit confusing, I have recently become interesting in clustering metrics and evaluation. In this post, I’ll work through a couple papers on...

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